Mandestrobin is a new systemic and translaminar fungicide being developed by Syngenta for the control of Botrytis and other foliar diseases of ornamental horticulture crops. The IR-4 Project completed 18 crop safety trials on 17 ornamental horticulture plant species or genera during 2015 to 2017. In these trials, all 17 species or genera exhibited minimal or no injury in the limited number of trials (one or two) for each crop; Syngenta can consider adding these to the label.